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Target
DNA polymerase beta
Ligand
BDBM50020661
Substrate
n/a
Meas. Tech.
ChEMBL_1361926 (CHEMBL3293530)
IC50
37900±n/a nM
Citation
 Le, DH; Takenaka, Y; Hamada, N; Mizushina, Y; Tanahashi, T Polyketides from the cultured lichen mycobiont of a Vietnamese Pyrenula sp. J Nat Prod 77:1404-12 (2014) [PubMed]  Article 
Target
Name:
DNA polymerase beta
Synonyms:
DNA Polymerase beta | DPOLB_RAT | Polb
Type:
PROTEIN
Mol. Mass.:
38334.34
Organism:
Rattus norvegicus
Description:
ChEMBL_1361926
Residue:
335
Sequence:
MSKRKAPQETLNGGITDMLVELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVTGIGPSAARKLVDEGIKTLEDLRKNEDKLNHHQRIGLKYFEDFEKRIPREEMLQMQDIVLNEVKKLDPEYIATVCGSFRRGAESSGDMDVLLTHPNFTSESSKQPKLLHRVVEQLQKVRFITDTLSKGETKFMGVCQLPSENDENEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEQDIFDYIQWRYREPKDRSE
  
Inhibitor
Name:
BDBM50020661
Synonyms:
CHEMBL3290500
Type:
Small organic molecule
Emp. Form.:
C26H36O5
Mol. Mass.:
428.561
SMILES:
[H][C@@]12CC(C)=CC[C@@]1([H])[C@]1([H])[C@H](O)[C@H](O[C@]3([H])[C@H](C)CCO[C@@]3(C)[C@]1([H])C(C)=C2)\C=C\C=C\C(O)=O |r,c:4,30|
Structure:
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