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Target
Matrix protein 2
Ligand
BDBM50020751
Substrate
n/a
Meas. Tech.
ChEMBL_1364624 (CHEMBL3291757)
IC50
1500±n/a nM
Citation
 Rey-Carrizo, M; Barniol-Xicota, M; Ma, C; Frigolé-Vivas, M; Torres, E; Naesens, L; Llabrés, S; Juárez-Jiménez, J; Luque, FJ; DeGrado, WF; Lamb, RA; Pinto, LH; Vázquez, S Easily accessible polycyclic amines that inhibit the wild-type and amantadine-resistant mutants of the M2 channel of influenza A virus. J Med Chem 57:5738-47 (2014) [PubMed]  Article 
Target
Name:
Matrix protein 2
Synonyms:
M | M2_I72A8 | Proton channel protein M2
Type:
PROTEIN
Mol. Mass.:
11180.06
Organism:
Influenza A virus (A/Udorn/307/1972(H3N2))
Description:
ChEMBL_22
Residue:
97
Sequence:
MSLLTEVETPIRNEWGCRCNDSSDPLVVAASIIGILHLILWILDRLFFKCIYRFFEHGLKRGPSTEGVPESMREEYRKEQQSAVDADDSHFVSIELE
  
Inhibitor
Name:
BDBM50020751
Synonyms:
CHEMBL3286971
Type:
Small organic molecule
Emp. Form.:
C12H18ClN3
Mol. Mass.:
239.744
SMILES:
Cl.NC(=N)N1CC2C(C1)C1C=CC2C2CC12 |c:10,TLB:5:6:10.11:13.15,THB:8:7:10.11:13.15,14:15:10.11:7.6|
Structure:
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