Target
Matrix protein 2
Ligand
BDBM50020754
Substrate
n/a
Meas. Tech.
ChEMBL_1364624 (CHEMBL3291757)
IC50
5540±n/a nM
Citation
 Rey-Carrizo, MBarniol-Xicota, MMa, CFrigolé-Vivas, MTorres, ENaesens, LLlabrés, SJuárez-Jiménez, JLuque, FJDeGrado, WFLamb, RAPinto, LHVázquez, S Easily accessible polycyclic amines that inhibit the wild-type and amantadine-resistant mutants of the M2 channel of influenza A virus. J Med Chem 57:5738-47 (2014) [PubMed]  Article 
Target
Name:
Matrix protein 2
Synonyms:
M | M2_I72A8 | Proton channel protein M2
Type:
PROTEIN
Mol. Mass.:
11180.06
Organism:
Influenza A virus (A/Udorn/307/1972(H3N2))
Description:
ChEMBL_22
Residue:
97
Sequence:
MSLLTEVETPIRNEWGCRCNDSSDPLVVAASIIGILHLILWILDRLFFKCIYRFFEHGLKRGPSTEGVPESMREEYRKEQQSAVDADDSHFVSIELE
  
Inhibitor
Name:
BDBM50020754
Synonyms:
CHEMBL3286976
Type:
Small organic molecule
Emp. Form.:
C12H16ClN
Mol. Mass.:
209.715
SMILES:
Cl.C1NCC2C1C1C=CC2C2C=CC12 |c:7,12,TLB:1:5:8.7:13.10,THB:3:4:8.7:13.10,11:10:8.7:4.5,12:13:8.7:4.5|
Structure:
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