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Target
Matrix protein 2
Ligand
BDBM50020855
Substrate
n/a
Meas. Tech.
ChEMBL_1364624 (CHEMBL3291757)
IC50
18000±n/a nM
Citation
 Rey-Carrizo, M; Barniol-Xicota, M; Ma, C; Frigolé-Vivas, M; Torres, E; Naesens, L; Llabrés, S; Juárez-Jiménez, J; Luque, FJ; DeGrado, WF; Lamb, RA; Pinto, LH; Vázquez, S Easily accessible polycyclic amines that inhibit the wild-type and amantadine-resistant mutants of the M2 channel of influenza A virus. J Med Chem 57:5738-47 (2014) [PubMed]  Article 
Target
Name:
Matrix protein 2
Synonyms:
M | M2_I72A8 | Proton channel protein M2
Type:
PROTEIN
Mol. Mass.:
11180.06
Organism:
Influenza A virus (A/Udorn/307/1972(H3N2))
Description:
ChEMBL_22
Residue:
97
Sequence:
MSLLTEVETPIRNEWGCRCNDSSDPLVVAASIIGILHLILWILDRLFFKCIYRFFEHGLKRGPSTEGVPESMREEYRKEQQSAVDADDSHFVSIELE
  
Inhibitor
Name:
BDBM50020855
Synonyms:
CHEMBL3286979
Type:
Small organic molecule
Emp. Form.:
C16H26ClN
Mol. Mass.:
267.837
SMILES:
Cl.CC12CC34CNCC33CC1(C)C(C)(C3)C2(C)C4 |TLB:15:12:9:4.2.3,17:4:9:12.14,1:2:9:12.14,THB:13:12:9:4.2.3,5:4:9:12.14,15:2:9:12.14,(12.35,-45.55,;1.02,-47.15,;2.11,-48.23,;4.17,-49.43,;6.28,-48.21,;7.75,-47.77,;8.65,-49.01,;7.75,-50.25,;6.27,-49.75,;3.97,-50.39,;2.14,-49.73,;.77,-50.51,;3.64,-49.73,;3.25,-51.26,;4.99,-50.51,;3.64,-48.23,;3.25,-46.75,;4.98,-47.46,)|
Structure:
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