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Target
Protein delta homolog 1
Ligand
BDBM50042940
Substrate
n/a
Meas. Tech.
ChEMBL_1444684 (CHEMBL3377246)
Ki
0.400000±n/a nM
Citation
 Abdel-Magid, AF Dual leucine zipper kinase inhibitors: potential treatments for neurodegenerative diseases. ACS Med Chem Lett 6:11-2 (2015) [PubMed]  Article 
Target
Name:
Protein delta homolog 1
Synonyms:
DLK | DLK-1 | DLK1 | DLK1_HUMAN | FA1 | Fetal antigen 1 | pG2
Type:
PROTEIN
Mol. Mass.:
41294.81
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1444684
Residue:
383
Sequence:
MTATEALLRVLLLLLAFGHSTYGAECFPACNPQNGFCEDDNVCRCQPGWQGPLCDQCVTSPGCLHGLCGEPGQCICTDGWDGELCDRDVRACSSAPCANNRTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDKTCSRPVTNCASSPCQNGGTCLQHTQVSYECLCKPEFTGLTCVKKRALSPQQVTRLPSGYGLAYRLTPGVHELPVQQPEHRILKVSMKELNKKTPLLTEGQAICFTILGVLTSLVVLGTVGIVFLNKCETWVSNLRYNHMLRKKKNLLLQYNSGEDLAVNIIFPEKIDMTTFSKEAGDEEI
  
Inhibitor
Name:
BDBM50042940
Synonyms:
CHEMBL3355005
Type:
Small organic molecule
Emp. Form.:
C22H24F3N5O
Mol. Mass.:
431.4541
SMILES:
[H][C@@]12CN(C[C@]1([H])[C@H]2c1cc(nn1C(C)C)-c1cnc2[nH]cc(c2c1)C(F)(F)F)C1COC1 |r|
Structure:
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