Reaction Details Report a problem with these data
Target
Similar to alpha-tubulin isoform 1
Ligand
BDBM50045302
Substrate
n/a
Meas. Tech.
ChEMBL_1458087 (CHEMBL3367650)
IC50
16790±n/a nM
Citation
 Li, YJ; Qin, YJ; Makawana, JA; Wang, YT; Zhang, YQ; Zhang, YL; Yang, MR; Jiang, AQ; Zhu, HL Synthesis, biological evaluation and molecular modeling of 1,3,4-thiadiazol-2-amide derivatives as novel antitubulin agents. Bioorg Med Chem 22:4312-22 (2014) [PubMed]  Article 
Target
Name:
Similar to alpha-tubulin isoform 1
Synonyms:
Similar to alpha-tubulin isoform 1
Type:
PROTEIN
Mol. Mass.:
10383.05
Organism:
Bos taurus
Description:
ChEMBL_104716
Residue:
99
Sequence:
CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
  
Inhibitor
Name:
BDBM50045302
Synonyms:
CHEMBL3310842
Type:
Small organic molecule
Emp. Form.:
C23H23Br2N3O7S
Mol. Mass.:
645.318
SMILES:
COc1cc(\C=C\c2nnc(NC(=O)c3cc(OC)c(OC)c(OC)c3Br)s2)c(Br)c(OC)c1OC
Structure:
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