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Target
Peroxisome proliferator-activated receptor gamma
Ligand
BDBM50046954
Substrate
n/a
Meas. Tech.
ChEMBL_1453700 (CHEMBL3364102)
EC50
900±n/a nM
Citation
 Liu, Q; Yang, QM; Hu, HJ; Yang, L; Yang, YB; Chou, GX; Wang, ZT Bioactive diterpenoids and flavonoids from the aerial parts of Scoparia dulcis. J Nat Prod 77:1594-600 (2014) [PubMed]  Article 
Target
Name:
Peroxisome proliferator-activated receptor gamma
Synonyms:
Nr1c3 | Nuclear receptor subfamily 1 group C member 3 | PPAR-gamma | PPARG_MOUSE | Pparg
Type:
PROTEIN
Mol. Mass.:
57593.55
Organism:
Mus musculus
Description:
ChEMBL_1453700
Residue:
505
Sequence:
MGETLGDSPVDPEHGAFADALPMSTSQEITMVDTEMPFWPTNFGISSVDLSVMEDHSHSFDIKPFTTVDFSSISAPHYEDIPFTRADPMVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNRPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKNIPGFINLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKNLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKVLQKMTDLRQIVTEHVQLLHVIKKTETDMSLHPLLQEIYKDLY
  
Inhibitor
Name:
BDBM50046954
Synonyms:
CHEMBL3314492
Type:
Small organic molecule
Emp. Form.:
C29H38O7
Mol. Mass.:
498.6078
SMILES:
[H][C@@]12[C@H](OC(=O)c3ccccc3)[C@@H](OC(C)=O)C(=C)[C@@H](CC\C(C)=C\CO)[C@@]1(C)CCC[C@]2(C)C(O)=O |r|
Structure:
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