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Target
Galectin-9
Ligand
BDBM50272150
Substrate
n/a
Meas. Tech.
ChEMBL_1454626 (CHEMBL3361815)
Kd
>5000000±n/a nM
Citation
 Rajput, VK; Leffler, H; Nilsson, UJ; Mukhopadhyay, B Synthesis and evaluation of iminocoumaryl and coumaryl derivatized glycosides as galectin antagonists. Bioorg Med Chem Lett 24:3516-20 (2014) [PubMed]  Article 
Target
Name:
Galectin-9
Synonyms:
LEG9_HUMAN | LGALS9
Type:
PROTEIN
Mol. Mass.:
39532.33
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1454626
Residue:
355
Sequence:
MAFSGSQAPYLSPAVPFSGTIQGGLQDGLQITVNGTVLSSSGTRFAVNFQTGFSGNDIAFHFNPRFEDGGYVVCNTRQNGSWGPEERKTHMPFQKGMPFDLCFLVQSSDFKVMVNGILFVQYFHRVPFHRVDTISVNGSVQLSYISFQNPRTVPVQPAFSTVPFSQPVCFPPRPRGRRQKPPGVWPANPAPITQTVIHTVQSAPGQMFSTPAIPPMMYPHPAYPMPFITTILGGLYPSKSILLSGTVLPSAQRFHINLCSGNHIAFHLNPRFDENAVVRNTQIDNSWGSEERSLPRKMPFVRGQSFSVWILCEAHCLKVAVDGQHLFEYYHRLRNLPTINRLEVGGDIQLTHVQT
  
Inhibitor
Name:
BDBM50272150
Synonyms:
CHEMBL500137 | N-benzyl-1-((2R,3R,4S,5R,6S)-3,5-dihydroxy-2-(hydroxymethyl)-6-(methylthio)-tetrahydro-2H-pyran-4-yl)-1H-1,2,3-triazole-4-carboxamide
Type:
Small organic molecule
Emp. Form.:
C17H22N4O5S
Mol. Mass.:
394.445
SMILES:
CS[C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1O)n1cc(nn1)C(=O)NCc1ccccc1 |r|
Structure:
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