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Target
Matrix protein 2 [1-96]
Ligand
BDBM50343549
Substrate
n/a
Meas. Tech.
ChEMBL_1453980 (CHEMBL3366674)
IC50
33500±n/a nM
Citation
 Torres, E; Leiva, R; Gazzarrini, S; Rey-Carrizo, M; Frigolé-Vivas, M; Moroni, A; Naesens, L; Vázquez, S Azapropellanes with anti-influenza a virus activity. ACS Med Chem Lett 5:831-6 (2014) [PubMed]  Article 
Target
Name:
Matrix protein 2 [1-96]
Synonyms:
M | M2_I72A2 | Matrix protein 2
Type:
PROTEIN
Mol. Mass.:
11051.96
Organism:
Influenza A virus
Description:
ChEMBL_1453980
Residue:
96
Sequence:
MSLLTEVETPIRNEWGCRCNDSSDPLVVAASIIGILHLILWILDRLFFKCIYRFFEHGLKRGPSTEGVPESMREEYRKEQQSAVDADDSHFVSIEL
  
Inhibitor
Name:
BDBM50343549
Synonyms:
3-Azahexacyclo[7.6.0.0(1,5).0(5,12).0(6,10).0(11,15)]pentadeca-7,13-diene Hydrochloride | CHEMBL1774319
Type:
Small organic molecule
Emp. Form.:
C14H15N
Mol. Mass.:
197.2756
SMILES:
C1NCC23C4C=CC5C4C4C(C=CC24)C135 |c:5,12,TLB:4:3:11.12:9,7:14:11.12:9,6:7:4:13.9,0:14:4:13.9,0:14:8:5.6,2:3:8:5.6,THB:8:9:14.3:11.12,12:13:4:14.7,12:13:4.8:14.10,13:3:8:5.6,10:14:4:13.9,10:9:4:14.7,10:14:8:5.6,9:8:14.3:5.6,0:14:11.12:9,2:3:11.12:9,(27.24,-25.38,;29.04,-26.14,;27.89,-24.75,;27.89,-22.62,;29.02,-21.83,;30.43,-22.65,;29.91,-23.76,;28.62,-23.1,;28.74,-20.39,;26.08,-20.42,;25.96,-23.13,;24.58,-23.82,;25.23,-22.66,;26.36,-21.86,;27.24,-23.79,)|
Structure:
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