Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50055448
Substrate
n/a
Meas. Tech.
ChEMBL_1450470 (CHEMBL3379966)
Ki
>10000±n/a nM
Citation
 Brizzi, A; Aiello, F; Marini, P; Cascio, MG; Corelli, F; Brizzi, V; De Petrocellis, L; Ligresti, A; Luongo, L; Lamponi, S; Maione, S; Pertwee, RG; Di Marzo, V Structure-affinity relationships and pharmacological characterization of new alkyl-resorcinol cannabinoid receptor ligands: Identification of a dual cannabinoid receptor/TRPA1 channel agonist. Bioorg Med Chem 22:4770-83 (2014) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50055448
Synonyms:
CHEMBL3323688
Type:
Small organic molecule
Emp. Form.:
C33H53NO3
Mol. Mass.:
511.7788
SMILES:
CCCCCCC(C)(C)c1cc(O)cc(OCCCCCCCC(=O)NC23CC4CC(CC(C4)C2)C3)c1 |TLB:25:26:29.28.33:31,THB:27:28:31:35.26.34,27:26:29.28.33:31,25:26:29:33.32.31,34:26:29:33.32.31,34:32:29:35.27.26|
Structure:
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