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Target
SPRY domain-containing SOCS box protein 2
Ligand
BDBM50055509
Substrate
n/a
Meas. Tech.
ChEMBL_1451373 (CHEMBL3363657)
Kd
4.4±n/a nM
Citation
 Yap, BK; Leung, EW; Yagi, H; Galea, CA; Chhabra, S; Chalmers, DK; Nicholson, SE; Thompson, PE; Norton, RS A potent cyclic peptide targeting SPSB2 protein as a potential anti-infective agent. J Med Chem 57:7006-15 (2014) [PubMed]  Article 
Target
Name:
SPRY domain-containing SOCS box protein 2
Synonyms:
GRCC9 | GRCC9 | Gene-rich cluster protein C9 | SPRY domain-containing SOCS box protein 2 | SPSB2 | SPSB2_HUMAN | SSB-2 | SSB2
Type:
PROTEIN
Mol. Mass.:
28636.12
Organism:
Homo sapiens (Human)
Description:
ChEMBL_109467
Residue:
263
Sequence:
MGQTALAGGSSSTPTPQALYPDLSCPEGLEELLSAPPPDLGAQRRHGWNPKDCSENIEVKEGGLYFERRPVAQSTDGARGKRGYSRGLHAWEISWPLEQRGTHAVVGVATALAPLQTDHYAALLGSNSESWGWDIGRGKLYHQSKGPGAPQYPAGTQGEQLEVPERLLVVLDMEEGTLGYAIGGTYLGPAFRGLKGRTLYPAVSAVWGQCQVRIRYLGERRAEPHSLLHLSRLCVRHNLGDTRLGQVSALPLPPAMKRYLLYQ
  
Inhibitor
Name:
BDBM50055509
Synonyms:
CHEMBL3326273
Type:
Small organic molecule
Emp. Form.:
C35H56N12O14S2
Mol. Mass.:
933.021
SMILES:
[H][C@]1(NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CSSC[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC1=O)C(N)=O)NC(C)=O)C(C)C)[C@@H](C)CC |r|
Structure:
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