Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50072349
Substrate
n/a
Meas. Tech.
ChEMBL_1469198 (CHEMBL3413754)
Ki
3.9±n/a nM
Citation
 Slavik, R; Herde, AM; Bieri, D; Weber, M; Schibli, R; Krämer, SD; Ametamey, SM; Mu, L Synthesis, radiolabeling and evaluation of novel 4-oxo-quinoline derivatives as PET tracers for imaging cannabinoid type 2 receptor. Eur J Med Chem 92:554-64 (2015) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50072349
Synonyms:
CHEMBL3409322
Type:
Small organic molecule
Emp. Form.:
C23H24Cl2N2O3
Mol. Mass.:
447.354
SMILES:
COc1ccc2n(C(=O)c3ccc(Cl)cc3Cl)c(C)c(CCN3CCOCC3)c2c1
Structure:
Search PDB for entries with ligand similarity: