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Target
Vasopressin V2 receptor
Ligand
BDBM50079263
Substrate
n/a
Meas. Tech.
ChEMBL_1472817 (CHEMBL3419479)
Ki
820±n/a nM
Citation
 Yoneda, T; Tabata, H; Tasaka, T; Oshitari, T; Takahashi, H; Natsugari, H N-benzoyl-1,5-benzothiazepine and its S-oxide as vasopressin receptor ligands: insight into the active stereochemistry around the seven-membered ring. J Med Chem 58:3268-73 (2015) [PubMed]  Article 
Target
Name:
Vasopressin V2 receptor
Synonyms:
ADHR | AVPR V2 | AVPR2 | Antidiuretic hormone receptor | DIR | DIR3 | Renal-type arginine vasopressin receptor | V2R | V2R_HUMAN | VASOPRESSIN V2 | Vasopressin V2 receptor | Vasopressin receptor
Type:
Receptor
Mol. Mass.:
40295.28
Organism:
Homo sapiens (Human)
Description:
P30518
Residue:
371
Sequence:
MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLVPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEAPLEGAPFVLLMLLASLNSCTNPWIYASFSSSVSSELRSLLCCARGRTPPSLGPQDESCTTASSSLAKDTSS
  
Inhibitor
Name:
BDBM50079263
Synonyms:
CHEMBL3416770
Type:
Small organic molecule
Emp. Form.:
C24H22N2O3S
Mol. Mass.:
418.508
SMILES:
Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1CCC[S@@+]([O-])c2ccccc12 |r|
Structure:
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