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Target
Cell division protein FtsZ
Ligand
BDBM50392993
Substrate
n/a
Meas. Tech.
ChEMBL_1470459 (CHEMBL3419176)
Kd
11000±n/a nM
Citation
 Li, X; Ma, S Advances in the discovery of novel antimicrobials targeting the assembly of bacterial cell division protein FtsZ. Eur J Med Chem 95:1-15 (2015) [PubMed]  Article 
Target
Name:
Cell division protein FtsZ
Synonyms:
FTSZ_MYCTU | ftsZ
Type:
PROTEIN
Mol. Mass.:
38736.30
Organism:
Mycobacterium tuberculosis
Description:
ChEMBL_1470459
Residue:
379
Sequence:
MTPPHNYLAVIKVVGIGGGGVNAVNRMIEQGLKGVEFIAINTDAQALLMSDADVKLDVGRDSTRGLGAGADPEVGRKAAEDAKDEIEELLRGADMVFVTAGEGGGTGTGGAPVVASIARKLGALTVGVVTRPFSFEGKRRSNQAENGIAALRESCDTLIVIPNDRLLQMGDAAVSLMDAFRSADEVLLNGVQGITDLITTPGLINVDFADVKGIMSGAGTALMGIGSARGEGRSLKAAEIAINSPLLEASMEGAQGVLMSIAGGSDLGLFEINEAASLVQDAAHPDANIIFGTVIDDSLGDEVRVTVIAAGFDVSGPGRKPVMGETGGAHRIESAKAGKLTSTLFEPVDAVSVPLHTNGATLSIGGDDDDVDVPPFMRR
  
Inhibitor
Name:
BDBM50392993
Synonyms:
TOTAROL
Type:
Small organic molecule
Emp. Form.:
C20H30O
Mol. Mass.:
286.4516
SMILES:
CC(C)c1c(O)ccc2c1CC[C@H]1C(C)(C)CCC[C@]21C |r|
Structure:
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