Reaction Details Report a problem with these data
Target
Cell division protein FtsZ
Ligand
BDBM50079357
Substrate
n/a
Meas. Tech.
ChEMBL_1470470 (CHEMBL3419187)
Kd
1500±n/a nM
Citation
 Li, X; Ma, S Advances in the discovery of novel antimicrobials targeting the assembly of bacterial cell division protein FtsZ. Eur J Med Chem 95:1-15 (2015) [PubMed]  Article 
Target
Name:
Cell division protein FtsZ
Synonyms:
FTSZ_BACSU | ftsZ
Type:
PROTEIN
Mol. Mass.:
40385.33
Organism:
Bacillus subtilis
Description:
ChEMBL_1470470
Residue:
382
Sequence:
MLEFETNIDGLASIKVIGVGGGGNNAVNRMIENEVQGVEYIAVNTDAQALNLSKAEVKMQIGAKLTRGLGAGANPEVGKKAAEESKEQIEEALKGADMVFVTAGMGGGTGTGAAPVIAQIAKDLGALTVGVVTRPFTFEGRKRQLQAAGGISAMKEAVDTLIVIPNDRILEIVDKNTPMLEAFREADNVLRQGVQGISDLIATPGLINLDFADVKTIMSNKGSALMGIGIATGENRAAEAAKKAISSPLLEAAIDGAQGVLMNITGGTNLSLYEVQEAADIVASASDQDVNMIFGSVINENLKDEIVVTVIATGFIEQEKDVTKPQRPSLNQSIKTHNQSVPKREPKREEPQQQNTVSRHTSQPADDTLDIPTFLRNRNKRG
  
Inhibitor
Name:
BDBM50079357
Synonyms:
CHEMBL3416826
Type:
Small organic molecule
Emp. Form.:
C15H8F3NO2S2
Mol. Mass.:
355.355
SMILES:
FC(F)(F)c1cccc(c1)-c1ccc(\C=C2\SC(=S)NC2=O)o1
Structure:
Search PDB for entries with ligand similarity: