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Target
Cell division protein FtsZ
Ligand
BDBM50079360
Substrate
n/a
Meas. Tech.
ChEMBL_1470447 (CHEMBL3418981)
IC50
12500±n/a nM
Citation
 Li, X; Ma, S Advances in the discovery of novel antimicrobials targeting the assembly of bacterial cell division protein FtsZ. Eur J Med Chem 95:1-15 (2015) [PubMed]  Article 
Target
Name:
Cell division protein FtsZ
Synonyms:
FTSZ_ECOLI | ftsZ | sfiB | sulB
Type:
Protein
Mol. Mass.:
40305.83
Organism:
Escherichia coli
Description:
P0A9A6
Residue:
383
Sequence:
MFEPMELTNDAVIKVIGVGGGGGNAVEHMVRERIEGVEFFAVNTDAQALRKTAVGQTIQIGSGITKGLGAGANPEVGRNAADEDRDALRAALEGADMVFIAAGMGGGTGTGAAPVVAEVAKDLGILTVAVVTKPFNFEGKKRMAFAEQGITELSKHVDSLITIPNDKLLKVLGRGISLLDAFGAANDVLKGAVQGIAELITRPGLMNVDFADVRTVMSEMGYAMMGSGVASGEDRAEEAAEMAISSPLLEDIDLSGARGVLVNITAGFDLRLDEFETVGNTIRAFASDNATVVIGTSLDPDMNDELRVTVVATGIGMDKRPEITLVTNKQVQQPVMDRYQQHGMAPLTQEQKPVAKVVNDNAPQTAKEPDYLDIPAFLRKQAD
  
Inhibitor
Name:
BDBM50079360
Synonyms:
CHEBI:69681 | Dichamanetin
Type:
Small organic molecule
Emp. Form.:
C29H24O6
Mol. Mass.:
468.4973
SMILES:
Oc1ccccc1Cc1c(O)c(Cc2ccccc2O)c2O[C@@H](CC(=O)c2c1O)c1ccccc1 |r|
Structure:
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