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Target
Matrix protein 2 [1-96]
Ligand
BDBM50079994
Substrate
n/a
Meas. Tech.
ChEMBL_1471017 (CHEMBL3420249)
IC50
22600±n/a nM
Citation
 Rey-Carrizo, M; Gazzarrini, S; Llabrés, S; Frigolé-Vivas, M; Juárez-Jiménez, J; Font-Bardia, M; Naesens, L; Moroni, A; Luque, FJ; Vázquez, S New polycyclic dual inhibitors of the wild type and the V27A mutant M2 channel of the influenza A virus with unexpected binding mode. Eur J Med Chem 96:318-29 (2015) [PubMed]  Article 
Target
Name:
Matrix protein 2 [1-96]
Synonyms:
M | M2_I72A2 | Matrix protein 2
Type:
PROTEIN
Mol. Mass.:
11051.96
Organism:
Influenza A virus
Description:
ChEMBL_1453980
Residue:
96
Sequence:
MSLLTEVETPIRNEWGCRCNDSSDPLVVAASIIGILHLILWILDRLFFKCIYRFFEHGLKRGPSTEGVPESMREEYRKEQQSAVDADDSHFVSIEL
  
Inhibitor
Name:
BDBM50079994
Synonyms:
CHEMBL3305169
Type:
Small organic molecule
Emp. Form.:
C13H21N3
Mol. Mass.:
219.3259
SMILES:
NC(=N)N1CC2C(C1)C1CCC2C2CCC12 |TLB:7:6:10.9:15.12,THB:4:5:10.9:15.12,13:12:10.9:5.6,14:15:10.9:5.6|
Structure:
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