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Target
Reverse transcriptase
Ligand
BDBM50084418
Substrate
n/a
Meas. Tech.
ChEMBL_1477014 (CHEMBL3427867)
IC50
34000±n/a nM
Citation
 Ma, J; Pawar, RS; Grundel, E; Mazzola, EP; Ridge, CD; Masaoka, T; Le Grice, SF; Wilson, J; Beutler, JA; Krynitsky, AJ Sesquiterpenoid tropolone glycosides from Liriosma ovata. J Nat Prod 78:315-9 (2015) [PubMed]  Article 
Target
Name:
Reverse transcriptase
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
29598.37
Organism:
Human immunodeficiency virus 1
Description:
Q9WKE8
Residue:
254
Sequence:
PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVFAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVN
  
Inhibitor
Name:
BDBM50084418
Synonyms:
CHEMBL3426555
Type:
Small organic molecule
Emp. Form.:
C27H36O11
Mol. Mass.:
536.5681
SMILES:
CC(=C)[C@@H]1CCc2cc(O[C@@H]3O[C@H](COC(=O)CC(C)(O)CC(O)=O)[C@@H](O)[C@H](O)[C@H]3O)c(=O)cc(C)c2C1 |r|
Structure:
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