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Target
X-box-binding protein 1
Ligand
BDBM50117871
Substrate
n/a
Meas. Tech.
ChEMBL_1516166 (CHEMBL3616012)
EC50
2.3±n/a nM
Citation
 Zhang, ZH; Zhang, HJ; Deng, AJ; Wang, B; Li, ZH; Liu, Y; Wu, LQ; Wang, WJ; Qin, HL Synthesis and Structure-Activity Relationships of Quaternary Coptisine Derivatives as Potential Anti-ulcerative Colitis Agents. J Med Chem 58:7557-71 (2015) [PubMed]  Article 
Target
Name:
X-box-binding protein 1
Synonyms:
TREB5 | XBP1 | XBP1_HUMAN | XBP2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28704.14
Organism:
Homo sapiens (Human)
Description:
gi_47678753
Residue:
261
Sequence:
MVVVAAAPNPADGTPKVLLLSGQPASAAGAPAGQALPLMVPAQRGASPEAASGGLPQARKRQRLTHLSPEEKALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLENQLLREKTHGLVVENQELRQRLGMDALVAEEEAEAKGNEVRPVAGSAESAALRLRAPLQQVQAQLSPLQNISPWILAVLTLQIQSLISCWAFWTTWTQSCSSNALPQSLPAWRSSQRSTQKDPVPYQPPFLCQWGRHQPSWKPLMN
  
Inhibitor
Name:
BDBM50117871
Synonyms:
CHEMBL3331117
Type:
Small organic molecule
Emp. Form.:
C19H15NO4
Mol. Mass.:
321.3267
SMILES:
C1Oc2cc3CCN4Cc5c6OCOc6ccc5C=C4c3cc2O1 |c:20|
Structure:
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