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Target
D(3) dopamine receptor
Ligand
BDBM50142753
Substrate
n/a
Meas. Tech.
ChEMBL_1552597 (CHEMBL3762402)
Ki
1.8±n/a nM
Citation
 Capet, M; Calmels, T; Levoin, N; Danvy, D; Berrebi-Bertrand, I; Stark, H; Schwartz, JC; Lecomte, JM Improving selectivity of dopamine D3 receptor ligands. Bioorg Med Chem Lett 26:885-8 (2016) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50142753
Synonyms:
CHEMBL3760063
Type:
Small organic molecule
Emp. Form.:
C20H32N4O3
Mol. Mass.:
376.4931
SMILES:
COc1ccccc1N1CCN(CCCCNC(=O)N2CCOCC2)CC1
Structure:
Search PDB for entries with ligand similarity: