Reaction Details Report a problem with these data
Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50441937
Substrate
n/a
Meas. Tech.
ChEMBL_1555061 (CHEMBL3767807)
Ki
2435±n/a nM
Citation
 Abate, C; Riganti, C; Pati, ML; Ghigo, D; Berardi, F; Mavlyutov, T; Guo, LW; Ruoho, A Development of sigma-1 (s1) receptor fluorescent ligands as versatile tools to studys1 receptors. Eur J Med Chem 108:577-85 (2016) [PubMed]  Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein
Type:
Protein
Mol. Mass.:
25307.17
Organism:
Cavia porcellus (Guinea pig)
Description:
Q60492
Residue:
223
Sequence:
MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSKLIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50441937
Synonyms:
CHEMBL2437387
Type:
Small organic molecule
Emp. Form.:
C24H30N2O4
Mol. Mass.:
410.506
SMILES:
COc1cccc2C(=O)N(CCCN3CCc4cc(OC)c(OC)cc4C3)CCc12
Structure:
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