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Target
Trace amine-associated receptor 1
Ligand
BDBM109570
Substrate
n/a
Meas. Tech.
ChEMBL_1563111 (CHEMBL3783759)
EC50
1.000000±n/a nM
Citation
 Galley, G; Beurier, A; Décoret, G; Goergler, A; Hutter, R; Mohr, S; Pähler, A; Schmid, P; Türck, D; Unger, R; Zbinden, KG; Hoener, MC; Norcross, RD Discovery and Characterization of 2-Aminooxazolines as Highly Potent, Selective, and Orally Active TAAR1 Agonists. ACS Med Chem Lett 7:192-7 (2016) [PubMed]  Article 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TAAR1_RAT | Ta1 | Taar1 | Tar1 | Trace amine receptor 1 (TARR1) | Trace amine-associated receptor 1 | Trace amine-associated receptor 1 (TAAR1) | Trace amine-associated receptor1 | Trar1
Type:
Enzyme
Mol. Mass.:
38034.73
Organism:
Rattus norvegicus (Rat)
Description:
Q923Y9
Residue:
332
Sequence:
MHLCHNSANISHTNSNWSRDVRASLYSLISLIILTTLVGNLIVIISISHFKQLHTPTNWLLHSMAVVDFLLGCLVMPYSMVRTVEHCWYFGELFCKLHTSTDIMLSSASILHLAFISIDRYYAVCDPLRYKAKINLAAIFVMILISWSLPAVFAFGMIFLELNLEGVEELYHNQVFCLRGCFPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRANLQVGLEGESRAPQSKETKAAKTLGIMVGVFLLCWCPFFFCMVLDPFLGYVIPPTLNDTLNWFGYLNSAFNPMVYAFFYPWFRRALKMVLFGKIFQKDSSRSKLFL
  
Inhibitor
Name:
BDBM109570
Synonyms:
US8604061, 364
Type:
Small organic molecule
Emp. Form.:
C11H13ClN2O
Mol. Mass.:
224.687
SMILES:
CCc1cc(Cl)ccc1[C@H]1COC(N)=N1 |r,c:14|
Structure:
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