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Target
Metallo-beta-lactamase type 2
Ligand
BDBM50129081
Substrate
n/a
Meas. Tech.
ChEMBL_1567671 (CHEMBL3792099)
Kd
806000±n/a nM
Citation
 Christopeit, T; Leiros, HK Fragment-based discovery of inhibitor scaffolds targeting the metallo-ß-lactamases NDM-1 and VIM-2. Bioorg Med Chem Lett 26:1973-7 (2016) [PubMed]  Article 
Target
Name:
Metallo-beta-lactamase type 2
Synonyms:
B2 metallo-beta-lactamase | BLAN1_KLEPN | Beta-lactamase NDM-1 | Beta-lactamase type II | Metallo-beta-lactamase NDM-1 | Metallo-beta-lactamase type 2 | Metallo-beta-lactamase type II | NDM-1 | New Delhi metallo-beta-lactamase-1 | blaNDM-1
Type:
PROTEIN
Mol. Mass.:
28498.15
Organism:
Klebsiella pneumoniae
Description:
ChEMBL_103887
Residue:
270
Sequence:
MELPNIMHPVAKLSTALAAALMLSGCMPGEIRPTIGQQMETGDQRFGDLVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLVVDTAWTDDQTAQILNWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPQEGMVAAQHSLTFAANGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIKDSKAKSLGNLGDADTEHYAASARAFGAAFPKASMIVMSHSAPDSRAAITHTARMADKLR
  
Inhibitor
Name:
BDBM50129081
Synonyms:
CHEBI:33070 | Indole-3-Butyric Acid
Type:
Small organic molecule
Emp. Form.:
C12H13NO2
Mol. Mass.:
203.2371
SMILES:
OC(=O)CCCc1c[nH]c2ccccc12
Structure:
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