Reaction Details Report a problem with these data
Target
P2Y purinoceptor 12
Ligand
BDBM50167273
Substrate
n/a
Meas. Tech.
ChEMBL_1573770 (CHEMBL3802954)
IC50
5.3±n/a nM
Citation
 Zetterberg, F; Svensson, P State of affairs: Design and structure-activity relationships of reversible P2Y12 receptor antagonists. Bioorg Med Chem Lett 26:2739-2754 (2016) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 12
Synonyms:
ADP-glucose receptor | ADPG-R | HORK3 | P2RY12 | P2T(AC) | P2Y purinoceptor 12 | P2Y(AC) | P2Y(ADP) | P2Y(cyc) | P2Y12 | P2Y12 platelet ADP receptor | P2Y12_HUMAN | Purinergic receptor P2Y12 | SP1999
Type:
Enzyme
Mol. Mass.:
39458.48
Organism:
Homo sapiens (Human)
Description:
Q9H244
Residue:
342
Sequence:
MQAVDNLTSAPGNTSLCTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITIDRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFIIIAVFFICFVPFHFARIPYTLSQTRDVFDCTAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM
  
Inhibitor
Name:
BDBM50167273
Synonyms:
CHEMBL3797316
Type:
Small organic molecule
Emp. Form.:
C27H34N4O9
Mol. Mass.:
558.5803
SMILES:
CCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(O)=O)NC(=O)c1cc(OC(C)(C)C(O)=O)c2ccc(C)cc2n1 |r|
Structure:
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