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Target
Metallo-beta-lactamase type 2
Ligand
BDBM50131078
Substrate
n/a
Meas. Tech.
ChEMBL_1581522 (CHEMBL3812664)
Ki
76000±n/a nM
Citation
 Christopeit, T; Albert, A; Leiros, HS Discovery of a novel covalent non-ß-lactam inhibitor of the metallo-ß-lactamase NDM-1. Bioorg Med Chem 24:2947-2953 (2016) [PubMed]  Article 
Target
Name:
Metallo-beta-lactamase type 2
Synonyms:
B2 metallo-beta-lactamase | BLAN1_KLEPN | Beta-lactamase NDM-1 | Beta-lactamase type II | Metallo-beta-lactamase NDM-1 | Metallo-beta-lactamase type 2 | Metallo-beta-lactamase type II | NDM-1 | New Delhi metallo-beta-lactamase-1 | blaNDM-1
Type:
PROTEIN
Mol. Mass.:
28498.15
Organism:
Klebsiella pneumoniae
Description:
ChEMBL_103887
Residue:
270
Sequence:
MELPNIMHPVAKLSTALAAALMLSGCMPGEIRPTIGQQMETGDQRFGDLVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLVVDTAWTDDQTAQILNWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPQEGMVAAQHSLTFAANGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIKDSKAKSLGNLGDADTEHYAASARAFGAAFPKASMIVMSHSAPDSRAAITHTARMADKLR
  
Inhibitor
Name:
BDBM50131078
Synonyms:
3-formylchromones | 4-Oxo-4H-chromene-3-carbaldehyde | CHEMBL86905
Type:
Small organic molecule
Emp. Form.:
C10H6O3
Mol. Mass.:
174.1528
SMILES:
O=Cc1coc2ccccc2c1=O
Structure:
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