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Target
C-C chemokine receptor type 9
Ligand
BDBM50178711
Substrate
n/a
Meas. Tech.
ChEMBL_1583874 (CHEMBL3815306)
IC50
85±n/a nM
Citation
 Pandya, BA; Baber, C; Chan, A; Chamberlain, B; Chandonnet, H; Goss, J; Hopper, T; Lippa, B; Poutsiaka, K; Romero, J; Stucka, S; Varoglu, M; Zhang, J; Zhang, X Discovery of indole inhibitors of chemokine receptor 9 (CCR9). Bioorg Med Chem Lett 26:3322-3325 (2016) [PubMed]  Article 
Target
Name:
C-C chemokine receptor type 9
Synonyms:
CCR9 | CCR9_HUMAN | GPR28
Type:
PROTEIN
Mol. Mass.:
42023.90
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1510356
Residue:
369
Sequence:
MTPTDFTSPIPNMADDYGSESTSSMEDYVNFNFTDFYCEKNNVRQFASHFLPPLYWLVFIVGALGNSLVILVYWYCTRVKTMTDMFLLNLAIADLLFLVTLPFWAIAAADQWKFQTFMCKVVNSMYKMNFYSCVLLIMCISVDRYIAIAQAMRAHTWREKRLLYSKMVCFTIWVLAAALCIPEILYSQIKEESGIAICTMVYPSDESTKLKSAVLTLKVILGFFLPFVVMACCYTIIIHTLIQAKKSSKHKALKVTITVLTVFVLSQFPYNCILLVQTIDAYAMFISNCAVSTNIDICFQVTQTIAFFHSCLNPVLYVFVGERFRRDLVKTLKNLGCISQAQWVSFTRREGSLKLSSMLLETTSGALSL
  
Inhibitor
Name:
BDBM50178711
Synonyms:
CHEMBL3814176
Type:
Small organic molecule
Emp. Form.:
C21H23NO2
Mol. Mass.:
321.4128
SMILES:
Cc1ccc2cc(C(O)=O)n(Cc3ccc(cc3)C(C)(C)C)c2c1
Structure:
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