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Target
RYamide receptor
Ligand
BDBM50192742
Substrate
n/a
Meas. Tech.
ChEMBL_1613599 (CHEMBL3855399)
EC50
20900±n/a nM
Citation
 Yoon, YK; Kim, JH; Kim, JH; Kwon, JY; Kim, YC; Kim, YJ; Park, ZY Pyrazolodiazepine derivatives with agonist activity toward Drosophila RYamide receptor. Bioorg Med Chem Lett 26:5116-5118 (2016) [PubMed]  Article 
Target
Name:
RYamide receptor
Synonyms:
NPY-R | NepYr | Neuropeptide Y-like receptor | RYAR_DROME | RYa-R | RYamide receptor | Synonyms=NepYr
Type:
PROTEIN
Mol. Mass.:
53538.04
Organism:
Drosophila melanogaster
Description:
ChEMBL_116973
Residue:
464
Sequence:
MEHHNSHLLPGGSEKMYYIAHQQPMLRNEDDNYQEGYFIRPDPASLIYNTTALPADDEGSNYGYGSTTTLSGLQFETYNITVMMNFSCDDYDLLSEDMWSSAYFKIIVYMLYIPIFIFALIGNGTVCYIVYSTPRMRTVTNYFIASLAIGDILMSFFCVPSSFISLFILNYWPFGLALCHFVNYSQAVSVLVSAYTLVAISIDRYIAIMWPLKPRITKRYATFIIAGVWFIALATALPIPIVSGLDIPMSPWHTKCEKYICREMWPSRTQEYYYTLSLFALQFVVPLGVLIFTYARITIRVWAKRPPGEAETNRDQRMARSKRKMVKMMLTVVIVFTCCWLPFNILQLLLNDEEFAHWDPLPYVWFAFHWLAMSHCCYNPIIYCYMNARFRSGFVQLMHRMPGLRRWCCLRSVGDRMNATSGTGPALPLNRMNTSTTYISARRKPRATSLRANPLSCGETSPLR
  
Inhibitor
Name:
BDBM50192742
Synonyms:
CHEMBL3982272
Type:
Small organic molecule
Emp. Form.:
C21H39N7OS
Mol. Mass.:
437.646
SMILES:
CC(C)CN1C[C@@H](CCCCN)N=C(SCCC(=O)NN)c2nn(CC(C)C)cc12 |r,t:12|
Structure:
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