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Target
RYamide receptor
Ligand
BDBM50192747
Substrate
n/a
Meas. Tech.
ChEMBL_1613599 (CHEMBL3855399)
EC50
5900±n/a nM
Citation
 Yoon, YK; Kim, JH; Kim, JH; Kwon, JY; Kim, YC; Kim, YJ; Park, ZY Pyrazolodiazepine derivatives with agonist activity toward Drosophila RYamide receptor. Bioorg Med Chem Lett 26:5116-5118 (2016) [PubMed]  Article 
Target
Name:
RYamide receptor
Synonyms:
NPY-R | NepYr | Neuropeptide Y-like receptor | RYAR_DROME | RYa-R | RYamide receptor | Synonyms=NepYr
Type:
PROTEIN
Mol. Mass.:
53538.04
Organism:
Drosophila melanogaster
Description:
ChEMBL_116973
Residue:
464
Sequence:
MEHHNSHLLPGGSEKMYYIAHQQPMLRNEDDNYQEGYFIRPDPASLIYNTTALPADDEGSNYGYGSTTTLSGLQFETYNITVMMNFSCDDYDLLSEDMWSSAYFKIIVYMLYIPIFIFALIGNGTVCYIVYSTPRMRTVTNYFIASLAIGDILMSFFCVPSSFISLFILNYWPFGLALCHFVNYSQAVSVLVSAYTLVAISIDRYIAIMWPLKPRITKRYATFIIAGVWFIALATALPIPIVSGLDIPMSPWHTKCEKYICREMWPSRTQEYYYTLSLFALQFVVPLGVLIFTYARITIRVWAKRPPGEAETNRDQRMARSKRKMVKMMLTVVIVFTCCWLPFNILQLLLNDEEFAHWDPLPYVWFAFHWLAMSHCCYNPIIYCYMNARFRSGFVQLMHRMPGLRRWCCLRSVGDRMNATSGTGPALPLNRMNTSTTYISARRKPRATSLRANPLSCGETSPLR
  
Inhibitor
Name:
BDBM50192747
Synonyms:
CHEMBL3935892
Type:
Small organic molecule
Emp. Form.:
C31H42N6O4
Mol. Mass.:
562.703
SMILES:
Cc1noc(C)c1CN1CC(Cc2ccccc2)NC(=O)c2nn(CCC3CCN(CC3)C(=O)OC(C)(C)C)cc12
Structure:
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