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Target
5'-AMP-activated protein kinase subunit beta-1
Ligand
BDBM50195479
Substrate
n/a
Meas. Tech.
ChEMBL_1617780 (CHEMBL3859849)
EC50
<500±n/a nM
Citation
 Cameron, KO; Kurumbail, RG Recent progress in the identification of adenosine monophosphate-activated protein kinase (AMPK) activators. Bioorg Med Chem Lett 26:5139-5148 (2016) [PubMed]  Article 
Target
Name:
5'-AMP-activated protein kinase subunit beta-1
Synonyms:
5'-AMP-activated protein kinase subunit beta-1 | AAKB1_HUMAN | AMP-activated protein kinase alpha-2/beta-1/gamma-3 | AMPK | AMPK subunit beta-1 | AMPKb | PRKAB1
Type:
n/a
Mol. Mass.:
30380.94
Organism:
Homo sapiens (Human)
Description:
Q9Y478
Residue:
270
Sequence:
MGNTSSERAALERHGGHKTPRRDSSGGTKDGDRPKILMDSPEDADLFHSEEIKAPEKEEFLAWQHDLEVNDKAPAQARPTVFRWTGGGKEVYLSGSFNNWSKLPLTRSHNNFVAILDLPEGEHQYKFFVDGQWTHDPSEPIVTSQLGTVNNIIQVKKTDFEVFDALMVDSQKCSDVSELSSSPPGPYHQEPYVCKPEERFRAPPILPPHLLQVILNKDTGISCDPALLPEPNHVMLNHLYALSIKDGVMVLSATHRYKKKYVTTLLYKPI
  
Inhibitor
Name:
BDBM50195479
Synonyms:
CHEMBL3950376
Type:
Small organic molecule
Emp. Form.:
C21H15NO4
Mol. Mass.:
345.3481
SMILES:
OC(=O)c1c[nH]c2ccc(cc12)-c1ccc(cc1)-c1c(O)cccc1O
Structure:
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