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Target
Transient receptor potential cation channel subfamily V member 3
Ligand
BDBM50197958
Substrate
n/a
Meas. Tech.
ChEMBL_1620338 (CHEMBL3862621)
EC50
16000±n/a nM
Citation
 Pollastro, F; Golin, S; Chianese, G; Putra, MY; Schiano Moriello, A; De Petrocellis, L; García, V; Munoz, E; Taglialatela-Scafati, O; Appendino, G Neuroactive and Anti-inflammatory Frankincense Cembranes: A Structure-Activity Study. J Nat Prod 79:1762-8 (2016) [PubMed]  Article 
Target
Name:
Transient receptor potential cation channel subfamily V member 3
Synonyms:
TRPV3_MOUSE | Transient receptor potential cation channel subfamily V member 3 | Trpv3
Type:
PROTEIN
Mol. Mass.:
90658.79
Organism:
Mus musculus
Description:
ChEMBL_116963
Residue:
791
Sequence:
MNAHSKEMAPLMGKRTTAPGGNPVVLTEKRPADLTPTKKSAHFFLEIEGFEPNPTVTKTSPPIFSKPMDSNIRQCLSGNCDDMDSPQSPQDDVTETPSNPNSPSANLAKEEQRQKKKRLKKRIFAAVSEGCVEELRELLQDLQDLCRRRRGLDVPDFLMHKLTASDTGKTCLMKALLNINPNTKEIVRILLAFAEENDILDRFINAEYTEEAYEGQTALNIAIERRQGDITAVLIAAGADVNAHAKGVFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMENEQTDITSQDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRSGNWELETMRNNDGLTPLQLAAKMGKAEILKYILSREIKEKPLRSLSRKFTDWAYGPVSSSLYDLTNVDTTTDNSVLEIIVYNTNIDNRHEMLTLEPLHTLLHTKWKKFAKYMFFLSFCFYFFYNITLTLVSYYRPREDEDLPHPLALTHKMSWLQLLGRMFVLIWATCISVKEGIAIFLLRPSDLQSILSDAWFHFVFFVQAVLVILSVFLYLFAYKEYLACLVLAMALGWANMLYYTRGFQSMGMYSVMIQKVILHDVLKFLFVYILFLLGFGVALASLIEKCSKDKKDCSSYGSFSDAVLELFKLTIGLGDLNIQQNSTYPILFLFLLITYVILTFVLLLNMLIALMGETVENVSKESERIWRLQRARTILEFEKMLPEWLRSRFRMGELCKVADEDFRLCLRINEVKWTEWKTHVSFLNEDPGPIRRTADLNKIQDSSRSNSKTTLYAFDELDEFPETSV
  
Inhibitor
Name:
BDBM50197958
Synonyms:
CHEMBL3979367
Type:
Small organic molecule
Emp. Form.:
C22H36O3
Mol. Mass.:
348.5194
SMILES:
CC(C)[C@@]12CC[C@@](C)(O1)[C@H](CC\C(C)=C\CC\C(C)=C\C2)OC(C)=O |r,t:14,19|
Structure:
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