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Target
Heat sensitive channel TRPV3
Ligand
BDBM50197962
Substrate
n/a
Meas. Tech.
ChEMBL_1620335 (CHEMBL3862618)
IC50
57500±n/a nM
Citation
 Pollastro, F; Golin, S; Chianese, G; Putra, MY; Schiano Moriello, A; De Petrocellis, L; García, V; Munoz, E; Taglialatela-Scafati, O; Appendino, G Neuroactive and Anti-inflammatory Frankincense Cembranes: A Structure-Activity Study. J Nat Prod 79:1762-8 (2016) [PubMed]  Article 
Target
Name:
Heat sensitive channel TRPV3
Synonyms:
Heat sensitive channel TRPV3
Type:
PROTEIN
Mol. Mass.:
90273.53
Organism:
Rattus norvegicus
Description:
ChEMBL_116972
Residue:
791
Sequence:
MKAHPKEMVPLMGKRTTAPGGNPAVLTEKRPADLTPTKKSAHFFLEIEGFEPNPTVTKTSPPIFSKPMDSNIRQCLSGNCDDMDSPQSPQDDVTETPSNPNSPSANLAKEEQRQKKKRLKKCIFAAVSEGCVRELRELLQDLQELCRRRRGLDASDFLMHKLTASDTGKTCLMKALLNINPNTKEIVRILLAFAEENDILDRFINAEYTEEAYEGQTALNIAIERRQGDITAVLIAAGADVNAHAKGVFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMENEQTDITSQDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRSGNWELETMRNNDGLTPLQLAAKMGKAEILKYILGREIKEKPLRSLSRKFTDWAYGPVSSSLYDLTNVDTTTDNSVLEIIVYNTNIDNRHEVLTLEPLHTLLHMKWKKFAKYMFFLSFCFYFSYNITLTLVSYYRPREGEALPHPLALTHKMSWLQLLGRMFVLIWAMCISVKEGIAIFLLRPSDLQSILSDAWFHFVIFGQAVLVILSVFLYLFAYKEYLACLVLAMALGWANMLYYTRGFQSMGMYSVMIQKVILHDVLKFLFVYILFLLGFGVALASLIEKCSKDKKDCSSYGSFSDAVLELFKLTIGLGGLNIQQNSTYPILFLFLLITYVILTFVLLLNMLIALMGETAENVSKESERIWRLQRARTTLEFEKMLPEWLRSRFRMGELCKVADEDFRLCLRINEVKWTEWKTHVSFLNEDPGPIRRTADSNKIQDSSRSNSKTTLYAFDELDEFPETSV
  
Inhibitor
Name:
BDBM50197962
Synonyms:
CHEMBL3894504
Type:
Small organic molecule
Emp. Form.:
C20H30O2
Mol. Mass.:
302.451
SMILES:
[H][C@@]12CC\C(C)=C\[C@]3([H])OCC(C)=C3CC\C(C)=C\CC[C@]1(C)O2 |r,c:12,t:5,18|
Structure:
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