Reaction Details Report a problem with these data
Target
Free fatty acid receptor 3
Ligand
BDBM50200342
Substrate
n/a
Meas. Tech.
ChEMBL_1622016 (CHEMBL3864368)
EC50
>10000±n/a nM
Citation
 Krasavin, M; Lukin, A; Bagnyukova, D; Zhurilo, N; Zahanich, I; Zozulya, S; Ihalainen, J; Forsberg, MM; Lehtonen, M; Rautio, J; Moore, D; Tikhonova, IG Free fatty acid receptor 1 (GPR40) agonists containing spirocyclic periphery inspired by LY2881835. Bioorg Med Chem 24:5481-5494 (2016) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 3
Synonyms:
FFAR3 | FFAR3_HUMAN | GPR41
Type:
PROTEIN
Mol. Mass.:
38655.15
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1508992
Residue:
346
Sequence:
MDTGPDQSYFSGNHWFVFSVYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTASDLLLLLFLPFRMVEAANGMHWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPLWYKTRPRLGQAGLVSVACWLLASAHCSVVYVIEFSGDISHSQGTNGTCYLEFRKDQLAILLPVRLEMAVVLFVVPLIITSYCYSRLVWILGRGGSHRRQRRVAGLLAATLLNFLVCFGPYNVSHVVGYICGESPAWRIYVTLLSTLNSCVDPFVYYFSSSGFQADFHELLRRLCGLWGQWQQESSMELKEQKGGEEQRADRPAERKTSEHSQGCGTGGQVACAES
  
Inhibitor
Name:
BDBM50200342
Synonyms:
CHEMBL3893207
Type:
Small organic molecule
Emp. Form.:
C34H42ClNO5
Mol. Mass.:
580.154
SMILES:
Cl.COc1ccc(CC2CCOC3(CCN(Cc4ccc(COc5ccc(CCC(O)=O)cc5)cc4)CC3)C2)cc1
Structure:
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