Reaction Details Report a problem with these data
Target
Free fatty acid receptor 1
Ligand
BDBM50201680
Substrate
n/a
Meas. Tech.
ChEMBL_1623243 (CHEMBL3865595)
EC50
0.800000±n/a nM
Citation
 Agarwal, S; Sasane, S; Deshmukh, P; Rami, B; Bandyopadhyay, D; Giri, P; Giri, S; Jain, M; Desai, RC Identification of an Orally Efficacious GPR40/FFAR1 Receptor Agonist. ACS Med Chem Lett 7:1134-1138 (2016) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
31473.32
Organism:
Homo sapiens (Human)
Description:
O14842
Residue:
300
Sequence:
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
  
Inhibitor
Name:
BDBM50201680
Synonyms:
CHEMBL3922381
Type:
Small organic molecule
Emp. Form.:
C27H26F3NO3S
Mol. Mass.:
501.56
SMILES:
CC#C[C@@H](CC(O)=O)c1ccc(OCc2cccc(CN(Cc3ccsc3)CC(F)(F)F)c2)cc1 |r|
Structure:
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