Reaction Details Report a problem with these data
Target
Cell division protein FtsZ
Ligand
BDBM50201769
Substrate
n/a
Meas. Tech.
ChEMBL_1623495 (CHEMBL3865907)
IC50
37500±n/a nM
Citation
 Haranahalli, K; Tong, S; Ojima, I Recent advances in the discovery and development of antibacterial agents targeting the cell-division protein FtsZ. Bioorg Med Chem 24:6354-6369 (2016) [PubMed]  Article 
Target
Name:
Cell division protein FtsZ
Synonyms:
FTSZ_STAAU | ftsZ
Type:
Protein
Mol. Mass.:
41023.36
Organism:
Staphylococcus aureus
Description:
P0A031
Residue:
390
Sequence:
MLEFEQGFNHLATLKVIGVGGGGNNAVNRMIDHGMNNVEFIAINTDGQALNLSKAESKIQIGEKLTRGLGAGANPEIGKKAAEESREQIEDAIQGADMVFVTSGMGGGTGTGAAPVVAKIAKEMGALTVGVVTRPFSFEGRKRQTQAAAGVEAMKAAVDTLIVIPNDRLLDIVDKSTPMMEAFKEADNVLRQGVQGISDLIAVSGEVNLDFADVKTIMSNQGSALMGIGVSSGENRAVEAAKKAISSPLLETSIVGAQGVLMNITGGESLSLFEAQEAADIVQDAADEDVNMIFGTVINPELQDEIVVTVIATGFDDKPTSHGRKSGSTGFGTSVNTSSNATSKDESFTSNSSNAQATDSVSERTHTTKEDDIPSFIRNREERRSRRTRR
  
Inhibitor
Name:
BDBM50201769
Synonyms:
CHEMBL3416823
Type:
Small organic molecule
Emp. Form.:
C22H31N5
Mol. Mass.:
365.515
SMILES:
[H][C@@]12CCN(C[C@@H]1c1cc(nc(n1)-c1ccncc1)C(CC)CC)[C@@H](CN)C2 |r|
Structure:
Search PDB for entries with ligand similarity: