Reaction Details Report a problem with these data
Target
Beta-lactamase BRO-1
Ligand
BDBM50212646
Substrate
n/a
Meas. Tech.
ChEMBL_40225 (CHEMBL653998)
IC50
13.1±n/a nM
Citation
  TBA Bioorg Med Chem Lett 3:2247-2252 (1993)   
Target
Name:
Beta-lactamase BRO-1
Synonyms:
BLA1_MORCA | Beta-lactamase BRO-1 | Penicillinase | bla
Type:
PROTEIN
Mol. Mass.:
35383.81
Organism:
Moraxella catarrhalis
Description:
ChEMBL_104100
Residue:
313
Sequence:
MQRRHFLQKTLLALPIIFSGNLLTGCKTNLSDDYLPDDKITNNPNLLQNKLKEILPIWENKFNAKIGMTIIADNGELSSHRGNEYFPVNSTIKAFIASHILLLVDKEKLDLNEKIIIKESDLIEYSPVCKKYFDENKPISISELCEATITLSDNGSANILLDKIGGLTAFNQFLKEIGADMVLANNEPLLNRSHYGETSDTAKPIPYTKSLKALIVGNILSNQSKEQLITWLINDKVADNLLRKYLPKNWRIGDKTGTGSESKNIIAVIWNENNKPYFISLFITQPHDGKSLDFKNQKDEIMAQIGKEIYPFL
  
Inhibitor
Name:
BDBM50212646
Synonyms:
CHEMBL72972
Type:
Small organic molecule
Emp. Form.:
C15H15N3O5S2
Mol. Mass.:
381.427
SMILES:
[H][C@@]12CC(=O)N1[C@@H](C(O)=O)[C@](C)(CSc1nc3ccccc3[nH]1)S2(=O)=O
Structure:
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