Reaction Details Report a problem with these data
Target
Beta-lactamase BRO-1
Ligand
BDBM50212641
Substrate
n/a
Meas. Tech.
ChEMBL_40225 (CHEMBL653998)
IC50
10.7±n/a nM
Citation
  TBA Bioorg Med Chem Lett 3:2247-2252 (1993)   
Target
Name:
Beta-lactamase BRO-1
Synonyms:
BLA1_MORCA | Beta-lactamase BRO-1 | Penicillinase | bla
Type:
PROTEIN
Mol. Mass.:
35383.81
Organism:
Moraxella catarrhalis
Description:
ChEMBL_104100
Residue:
313
Sequence:
MQRRHFLQKTLLALPIIFSGNLLTGCKTNLSDDYLPDDKITNNPNLLQNKLKEILPIWENKFNAKIGMTIIADNGELSSHRGNEYFPVNSTIKAFIASHILLLVDKEKLDLNEKIIIKESDLIEYSPVCKKYFDENKPISISELCEATITLSDNGSANILLDKIGGLTAFNQFLKEIGADMVLANNEPLLNRSHYGETSDTAKPIPYTKSLKALIVGNILSNQSKEQLITWLINDKVADNLLRKYLPKNWRIGDKTGTGSESKNIIAVIWNENNKPYFISLFITQPHDGKSLDFKNQKDEIMAQIGKEIYPFL
  
Inhibitor
Name:
BDBM50212641
Synonyms:
Brobactam
Type:
Small organic molecule
Emp. Form.:
C8H10BrNO3S
Mol. Mass.:
280.139
SMILES:
[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2Br)C(O)=O
Structure:
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