Reaction Details Report a problem with these data
Target
Free fatty acid receptor 3
Ligand
BDBM50232522
Substrate
n/a
Meas. Tech.
ChEBML_1647944
EC50
>50000±n/a nM
Citation
 Sparks, SM; Aquino, C; Banker, P; Collins, JL; Cowan, D; Diaz, C; Dock, ST; Hertzog, DL; Liang, X; Swiger, ED; Yuen, J; Chen, G; Jayawickreme, C; Moncol, D; Nystrom, C; Rash, V; Rimele, T; Roller, S; Ross, S Exploration of phenylpropanoic acids as agonists of the free fatty acid receptor 4 (FFA4): Identification of an orally efficacious FFA4 agonist. Bioorg Med Chem Lett 27:1278-1283 (2017) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 3
Synonyms:
FFAR3 | FFAR3_HUMAN | GPR41
Type:
PROTEIN
Mol. Mass.:
38655.15
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1508992
Residue:
346
Sequence:
MDTGPDQSYFSGNHWFVFSVYLLTFLVGLPLNLLALVVFVGKLQRRPVAVDVLLLNLTASDLLLLLFLPFRMVEAANGMHWPLPFILCPLSGFIFFTTIYLTALFLAAVSIERFLSVAHPLWYKTRPRLGQAGLVSVACWLLASAHCSVVYVIEFSGDISHSQGTNGTCYLEFRKDQLAILLPVRLEMAVVLFVVPLIITSYCYSRLVWILGRGGSHRRQRRVAGLLAATLLNFLVCFGPYNVSHVVGYICGESPAWRIYVTLLSTLNSCVDPFVYYFSSSGFQADFHELLRRLCGLWGQWQQESSMELKEQKGGEEQRADRPAERKTSEHSQGCGTGGQVACAES
  
Inhibitor
Name:
BDBM50232522
Synonyms:
CHEMBL4065397
Type:
Small organic molecule
Emp. Form.:
C19H19F3O4
Mol. Mass.:
368.347
SMILES:
COc1ccc(cc1COc1ccc(CCC(O)=O)cc1C)C(F)(F)F
Structure:
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