Reaction Details Report a problem with these data
Target
Mu-type opioid receptor
Ligand
BDBM50019056
Substrate
n/a
Meas. Tech.
ChEMBL_1650831 (CHEMBL3999965)
Ki
684±n/a nM
Citation
 Rosa, M; Gonzalez-Nunez, V; Barreto-Valer, K; Marcelo, F; Sánchez-Sánchez, J; Calle, LP; Arévalo, JC; Rodríguez, RE; Jiménez-Barbero, J; Arsequell, G; Valencia, G Role of the sugar moiety on the opioid receptor binding and conformation of a series of enkephalin neoglycopeptides. Bioorg Med Chem 25:2260-2265 (2017) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
Mu opioid receptor-like OR2 | oprm1 | or2
Type:
PROTEIN
Mol. Mass.:
43012.33
Organism:
Danio rerio
Description:
ChEMBL_109864
Residue:
382
Sequence:
MMENTGNISDLLYALSNPMVSNSSIFCRNFSNSSGLVNMNSSVCDRTPELDKSSTPVIVAIIITALYSIVCVMGLVGNVLVMYVIIRYTKMKTATNIYIFNLALADSLATSTLPFQSVNYLMGTWPFGDELCKIVMSIDYYNMFTSIFTLTTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMVMASTTSDLHSNGIIDCTLLFPHPSWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIFVIIKALVTIPNSLLQTITWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCVPSPSVLDLQNSTRSRNPQRDGQSSGHTVDRTNQQV
  
Inhibitor
Name:
BDBM50019056
Synonyms:
(S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methylsulfanyl-butyric acid | ([Met]-enkephalin)2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methylsulfanyl-butyric acid([Met]-enkephalin | 2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-1-oxo-3-phenyl-propylamino]-4-methylsulfanyl-butyric acid | 2-[1-[1-amino-2-(4-hydroxyphenyl)-(1S)-ethylcarboxamidomethylcarboxamidomethylcarboxamido]-2-phenyl-(1S)-ethylcarboxamido]-4-methylsulfanyl-(2S)-butanoic acid | 2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methylsulfanyl-butyric acid | CHEMBL13786 | H-Tyr-Gly-Gly-Phe-Met-OH | Met5-Enkephalin | [Met5]-enkephalin | met-enkephalin
Type:
Small organic molecule
Emp. Form.:
C27H35N5O7S
Mol. Mass.:
573.661
SMILES:
CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O
Structure:
Search PDB for entries with ligand similarity: