Reaction Details Report a problem with these data
Target
Proteinase-activated receptor 2
Ligand
BDBM50233671
Substrate
n/a
Meas. Tech.
ChEMBL_1651136 (CHEMBL4000391)
EC50
20±n/a nM
Citation
 Yau, MK; Suen, JY; Xu, W; Lim, J; Liu, L; Adams, MN; He, Y; Hooper, JD; Reid, RC; Fairlie, DP Potent Small Agonists of Protease Activated Receptor 2. ACS Med Chem Lett 7:105-10 (2016) [PubMed]  Article 
Target
Name:
Proteinase-activated receptor 2
Synonyms:
F2RL1 | GPR11 | PAR2 | PAR2_HUMAN
Type:
PROTEIN
Mol. Mass.:
44152.54
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1497756
Residue:
397
Sequence:
MRSPSAAWLLGAAILLAASLSCSGTIQGTNRSSKGRSLIGKVDGTSHVTGKGVTVETVFSVDEFSASVLTGKLTTVFLPIVYTIVFVVGLPSNGMALWVFLFRTKKKHPAVIYMANLALADLLSVIWFPLKIAYHIHGNNWIYGEALCNVLIGFFYGNMYCSILFMTCLSVQRYWVIVNPMGHSRKKANIAIGISLAIWLLILLVTIPLYVVKQTIFIPALNITTCHDVLPEQLLVGDMFNYFLSLAIGVFLFPAFLTASAYVLMIRMLRSSAMDENSEKKRKRAIKLIVTVLAMYLICFTPSNLLLVVHYFLIKSQGQSHVYALYIVALCLSTLNSCIDPFVYYFVSHDFRDHAKNALLCRSVRTVKQMQVSLTSKKHSRKSSSYSSSSTTVKTSY
  
Inhibitor
Name:
BDBM50233671
Synonyms:
CHEMBL4100763
Type:
Small organic molecule
Emp. Form.:
C23H35N5O5
Mol. Mass.:
461.5545
SMILES:
NC(=O)CNC(=O)C(NC(=O)C(CC1CCCCC1)NC(=O)c1ccno1)C1CCCCC1
Structure:
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