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Target
Proteinase-activated receptor 2
Ligand
BDBM50329488
Substrate
n/a
Meas. Tech.
ChEMBL_1651136 (CHEMBL4000391)
EC50
200±n/a nM
Citation
 Yau, MK; Suen, JY; Xu, W; Lim, J; Liu, L; Adams, MN; He, Y; Hooper, JD; Reid, RC; Fairlie, DP Potent Small Agonists of Protease Activated Receptor 2. ACS Med Chem Lett 7:105-10 (2016) [PubMed]  Article 
Target
Name:
Proteinase-activated receptor 2
Synonyms:
F2RL1 | GPR11 | PAR2 | PAR2_HUMAN
Type:
PROTEIN
Mol. Mass.:
44152.54
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1497756
Residue:
397
Sequence:
MRSPSAAWLLGAAILLAASLSCSGTIQGTNRSSKGRSLIGKVDGTSHVTGKGVTVETVFSVDEFSASVLTGKLTTVFLPIVYTIVFVVGLPSNGMALWVFLFRTKKKHPAVIYMANLALADLLSVIWFPLKIAYHIHGNNWIYGEALCNVLIGFFYGNMYCSILFMTCLSVQRYWVIVNPMGHSRKKANIAIGISLAIWLLILLVTIPLYVVKQTIFIPALNITTCHDVLPEQLLVGDMFNYFLSLAIGVFLFPAFLTASAYVLMIRMLRSSAMDENSEKKRKRAIKLIVTVLAMYLICFTPSNLLLVVHYFLIKSQGQSHVYALYIVALCLSTLNSCIDPFVYYFVSHDFRDHAKNALLCRSVRTVKQMQVSLTSKKHSRKSSSYSSSSTTVKTSY
  
Inhibitor
Name:
BDBM50329488
Synonyms:
5-Isoxazoyl-Cha-Ile-(3-[aminomethyl]phenyl)-(4-[aminomethyl]-piperidin-1-yl)methanone | CHEMBL1269133
Type:
Small organic molecule
Emp. Form.:
C33H48N6O5
Mol. Mass.:
608.7714
SMILES:
CC[C@H](C)[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)c1ccno1)C(=O)NCc1cccc(c1)C(=O)N1CCC(CN)CC1 |r|
Structure:
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