Reaction Details Report a problem with these data
Target
Melatonin receptor
Ligand
BDBM85054
Substrate
n/a
Ki
2.9±n/a nM
Comments
PDSP_883
Citation
 Dubocovich, ML; Masana, MI; Iacob, S; Sauri, DM Melatonin receptor antagonists that differentiate between the human Mel1a and Mel1b recombinant subtypes are used to assess the pharmacological profile of the rabbit retina ML1 presynaptic heteroreceptor. Naunyn Schmiedebergs Arch Pharmacol 355:365-75 (1997) [PubMed]  Article 
Target
Name:
Melatonin receptor
Synonyms:
Melatonin | Melatonin receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
13287.02
Organism:
RABBIT
Description:
Q9BE38
Residue:
114
Sequence:
MIWMLTLVAVMPNLHTGTLQYDPRVYSCTFSQSVSSAYTIAVVVFHFIIPMLMSSCCYLRIWILVLQVRRRVKPDNKPKLKPQDFRNFITMFVVFVLFAICWAPLNFIVLLGRS
  
Inhibitor
Name:
BDBM85054
Synonyms:
1-[3-(5-Methoxy-1H-indol-3-yl)piperidino]ethanone | GR 128107
Type:
Small organic molecule
Emp. Form.:
C16H20N2O2
Mol. Mass.:
272.3422
SMILES:
COc1ccc2[nH]cc(C3CCCN(C3)C(C)=O)c2c1
Structure:
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