Reaction Details Report a problem with these data
Target
Galanin receptor type 2
Ligand
BDBM50273369
Substrate
n/a
Ki
0.85±n/a nM
Comments
PDSP_852
Citation
 Wang, S; Hashemi, T; He, C; Strader, C; Bayne, M Molecular cloning and pharmacological characterization of a new galanin receptor subtype. Mol Pharmacol 52:337-43 (1997) [PubMed]  Article 
Target
Name:
Galanin receptor type 2
Synonyms:
GALR2_RAT | Galanin R2 | Galanin receptor 2 | Galanin receptor type 2 | Galnr2 | Galr2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40697.04
Organism:
RAT
Description:
Galanin R2 GALR2 RAT::O08726
Residue:
372
Sequence:
MNGSGSQGAENTSQEGGSGGWQPEAVLVPLFFALIFLVGTVGNALVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDDWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLALLFSGPYLSYYRQSQLANLTVCHPAWSAPRRRAMDLCTFVFSYLLPVLVLSLTYARTLRYLWRTVDPVTAGSGSQRAKRKVTRMIIIVAVLFCLCWMPHHALILCVWFGRFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRKICAGLLRPAPRRASGRVSILAPGNHSGSMLEQESTDLTQVSEAAGPLVPPPALPNCTASSRTLDPAC
  
Inhibitor
Name:
BDBM50273369
Synonyms:
CHEMBL526003 | GWTLNSAGYLLGPQQFFGLM-CONH2 | Galanin (1-13)-SP-(5-11) | galantide
Type:
Small organic molecule
Emp. Form.:
C104H151N25O26S
Mol. Mass.:
2199.529
SMILES:
CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(N)=O |r|
Structure:
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