Reaction Details
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Prostaglandin F2-alpha receptor
Ligand
BDBM85175
Substrate
n/a
Ki
1700±n/a nM
Comments
PDSP_453
Citation
Kiriyama, M; Ushikubi, F; Kobayashi, T; Hirata, M; Sugimoto, Y; Narumiya, S Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells. Br J Pharmacol 122:217-24 (1997) [PubMed] Article More Info.:
Target
Name:
Prostaglandin F2-alpha receptor
Synonyms:
PF2R_MOUSE | ProstaglandinF2Alpha | Ptgfr
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40714.02
Organism:
MOUSE
Description:
ProstaglandinF2Alpha PTGFR MOUSE::P43117
Residue:
366
Sequence:
MSMNSSKQPVSPAAGLIANTTCQTENRLSVFFSIIFMTVGILSNSLAIAILMKAYQRFRQKSKASFLLLASGLVITDFFGHLINGGIAVFVYASDKDWIRFDQSNILCSIFGISMVFSGLCPLFLGSAMAIERCIGVTNPIFHSTKITSKHVKMILSGVCMFAVFVAVLPILGHRDYQIQASRTWCFYNTEHIEDWEDRFYLLFFSFLGLLALGVSFSCNAVTGVTLLRVKFRSQQHRQGRSHHLEMIIQLLAIMCVSCVCWSPFLVTMANIAINGNNSPVTCETTLFALRMATWNQILDPWVYILLRKAVLRNLYKLASRCCGVNIISLHIWELSSIKNSLKVAAISESPAAEKESQQASSEAGL
Inhibitor
Name:
BDBM85175
Synonyms:
BW245C | CAS_72814-32-5 | NSC_3080928
Type:
Small organic molecule
Emp. Form.:
C19H32N2O5
Mol. Mass.:
368.4678
SMILES:
OC(CCn1c(CCCCCCC(O)=O)c(O)[nH]c1=O)C1CCCCC1
Structure:
