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Target
Gamma-aminobutyric acid receptor subunit alpha-6
Ligand
BDBM23183
Substrate
n/a
Ki
5.37±n/a nM
Comments
PDSP_1260
Citation
 Ebert, B; Thompson, SA; Saounatsou, K; McKernan, R; Krogsgaard-Larsen, P; Wafford, KA Differences in agonist/antagonist binding affinity and receptor transduction using recombinant human gamma-aminobutyric acid type A receptors. Mol Pharmacol 52:1150-6 (1997) [PubMed] 
Target
Name:
Gamma-aminobutyric acid receptor subunit alpha-6
Synonyms:
GABA A alpha6 | GABA receptor alpha-6 subunit | GABRA6 | GBRA6_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51029.60
Organism:
Homo sapiens (Human)
Description:
GABA A alpha6 0 HUMAN::Q16445
Residue:
453
Sequence:
MASSLPWLCIILWLENALGKLEVEGNFYSENVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLTINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNLQTQKAKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRITSLSLPIVSSSEANKVLTRAPILQSTPVTPPPLSPAFGGTSKIDQYSRILFPVAFAGFNLVYWVVYLSKDTMEVSSSVE
  
Inhibitor
Name:
BDBM23183
Synonyms:
5-(aminomethyl)-1,2-oxazol-3-ol | Agarin | CHEMBL273481 | Muscimol | Pantherine
Type:
GABA Agonist
Emp. Form.:
C4H6N2O2
Mol. Mass.:
114.1026
SMILES:
NCc1cc(=O)[nH]o1
Structure:
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