Reaction Details
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Report a problem with these dataTarget
Glutamate receptor
Ligand
BDBM50013055
Substrate
n/a
Ki
31.13±n/a nM
Comments
PDSP_2014
Citation
Toms, NJ; Reid, ME; Phillips, W; Kemp, MC; Roberts, PJ A novel kainate receptor ligand [3H]-(2S,4R)-4-methylglutamate: pharmacological characterization in rabbit brain membranes. Neuropharmacology 36:1483-8 (1997) [PubMed] Article More Info.:
Target
Name:
Glutamate receptor
Synonyms:
Glutamate kainate | Glutamate-Kainate
Type:
Enzyme Catalytic Domain
Mol. Mass.:
96238.98
Organism:
RABBIT
Description:
Glutamate-Kainate Glutamate kainate RABBIT::G1SXH9
Residue:
849
Sequence:
MPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDLFYINLYPDYAAISRAVLDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDAKPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTEYYHYFFTTLDLFALDLELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVAIASHRASQLTVSSLQCHRHKPWRLGPRFMNLIKEAQWDGLTGRITFNKTDGLRKNFDLDIISLKEEGTEKAAGEVSKHLYKVWKKIGIWNSNSGLNMTEGNKDRSNNITDSLANRTLIVTTILEEPYVMYKKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDGKYGAQNDKGEWNGMVKELIDHKADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQTALVKNNDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEEDNKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSRKNNDVEQCLSFNAIMEELGISLKNQKKLKKKSRTKGKSSFTSILTCHQRRTQRKETVA
Inhibitor
Name:
BDBM50013055
Synonyms:
2-aminopentanedioateglutamate | L-Glutamate | glutamate(2-) | glutamic acid dianion
Type:
Small organic molecule
Emp. Form.:
C5H7NO4
Mol. Mass.:
145.1145
SMILES:
NC(CCC([O-])=O)C([O-])=O
Structure:
