Reaction Details Report a problem with these data
Target
Dihydroorotase
Ligand
BDBM85254
Substrate
n/a
Meas. Tech.
Inhibition Assay
pH
7.0000±0.0000
Ki
76000000±0 nM
Citation
 Li, Y; Raushel, FM Inhibitors designed for the active site of dihydroorotase. Bioorg Chem 33:470-83 (2005) [PubMed]  Article 
Target
Name:
Dihydroorotase
Synonyms:
Dihydroorotase (DHO) | pyrC | PYRC_ECOLI
Type:
Enzyme
Mol. Mass.:
38823.92
Organism:
Escherichia coli (strain K12)
Description:
P05020
Residue:
348
Sequence:
MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSIDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVKQ
  
Inhibitor
Name:
BDBM85254
Synonyms:
4,6-dioxo-piperidine-2-carboxylic acid, 3
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
[O-]C(=O)[C@@H]1CC(=O)CC(=O)N1 |r|
Structure:
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