Reaction Details Report a problem with these data
Target
Transmembrane and immunoglobulin domain-containing 3
Ligand
BDBM85618
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_2330
Citation
 Varani, K; Merighi, S; Gessi, S; Klotz, KN; Leung, E; Baraldi, PG; Cacciari, B; Romagnoli, R; Spalluto, G; Borea, PA [(3)H]MRE 3008F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A(3) adenosine receptors. Mol Pharmacol 57:968-75 (2000) [PubMed] 
Target
Name:
Transmembrane and immunoglobulin domain-containing 3
Synonyms:
ADENOSINE A3 | ADORA3 | Adora3 protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25707.75
Organism:
RAT
Description:
Q4V8H0
Residue:
232
Sequence:
MEPLLLLSLALFSDAMVMDEKVKSGVELDTASAICNYDAHYKDHTKYWCRGYFRDSCNIIAFTPNSSNRVALKDTGDQLIITVSCLVKEDTGWYWCGIQRDFARDDMDFTKLIVTDNREDRANGLSPGTSGNRTRSCKTSKAVQKAEGSRMSILIVCVLISGLGIIFLISHMSRGRRSQRNRGVTGKSINRNPQASQAPSMVSIPLTVLPKVPRQNGQQKALQWTGNATKTG
  
Inhibitor
Name:
BDBM85618
Synonyms:
CHEMBL302765 | J1.251.181G | MRE 3008F20
Type:
Small organic molecule
Emp. Form.:
C21H20N8O3
Mol. Mass.:
432.4353
SMILES:
CCCn1cc2c(n1)nc(NC(=O)Nc1ccc(OC)cc1)n1nc(nc21)-c1ccco1
Structure:
Search PDB for entries with ligand similarity: