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Target
Prostaglandin-H2 D-isomerase
Ligand
BDBM50008805
Substrate
n/a
Ki
0.49±n/a nM
Comments
PDSP_2289
Citation
 Arimura, A; Yasui, K; Kishino, J; Asanuma, F; Hasegawa, H; Kakudo, S; Ohtani, M; Arita, H Prevention of allergic inflammation by a novel prostaglandin receptor antagonist, S-5751. J Pharmacol Exp Ther 298:411-9 (2001) [PubMed] 
Target
Name:
Prostaglandin-H2 D-isomerase
Synonyms:
PGD2 | PTGDS | PTGDS_PIG
Type:
Enzyme Catalytic Domain
Mol. Mass.:
20572.78
Organism:
GUINEA PIG
Description:
PGD2 0 GUINEA PIG::Q29095
Residue:
189
Sequence:
MATPSSLWLGLALLGTLGVLQTPAQASLQPNFQEDKFLGRWFTSGLASNSSWFLEKKKVLSMCKSLVAPAPDGGFNLTSTFLRKDQCVTRTLMLRPAGPPGCYSYTSPHGGSNLEVSVVETDYKNYALLHTESGPSPGPAFRMATLYSRSQAPGAAVREKFTAFAKARGFTEDGIVFLPRNEKCLEEHE
  
Inhibitor
Name:
BDBM50008805
Synonyms:
7-(3-Benzenesulfonylamino-bicyclo[2.2.1]hept-2-yl)-hept-5-enoic acid | CHEMBL56941 | S 145 | S-145,(+)
Type:
Small organic molecule
Emp. Form.:
C20H27NO4S
Mol. Mass.:
377.498
SMILES:
OC(=O)CCC\C=C/C[C@H]1[C@@H]2CCC(C2)C1NS(=O)(=O)c1ccccc1
Structure:
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