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Target
Ionotropic glutamate receptor subunit Delta2
Ligand
BDBM50062599
Substrate
n/a
Ki
1000±n/a nM
Comments
PDSP_3005
Citation
 Williams, K; Dattilo, M; Sabado, TN; Kashiwagi, K; Igarashi, K Pharmacology of delta2 glutamate receptors: effects of pentamidine and protons. J Pharmacol Exp Ther 305:740-8 (2003) [PubMed]  Article 
Target
Name:
Ionotropic glutamate receptor subunit Delta2
Synonyms:
Glutamate delta 2 | Glutamate receptor delta-2 subunit
Type:
Enzyme Catalytic Domain
Mol. Mass.:
19076.25
Organism:
Xenopus
Description:
B9V8R6
Residue:
168
Sequence:
FDLSLWACIAGTVLLVGLLVYLLNWLNPPRLQMGSMTSTTLYNSMWFVYGSFVQQGGEVPYTTLATRMMMGAWWLFALIVISSYTANLAAFLTISRIESSIQSLQDLSRQTDIPYGTVFDSAVYEHVRVKGMNPFERDSMYSQMWRMINRSNGSENNVQESLEGIQKV
  
Inhibitor
Name:
BDBM50062599
Synonyms:
3,5-Dimethyl-adamantan-1-ylamine | CHEMBL807 | EN300-123026 | MEMANTINE | Namenda | US10214478, Compound memantine
Type:
Small organic molecule
Emp. Form.:
C12H21N
Mol. Mass.:
179.3018
SMILES:
CC12CC3CC(C)(C1)CC(N)(C3)C2 |TLB:7:1:4.5.8:11,10:9:4:2.7.1,0:1:4:8.9.11,THB:7:5:11:2.1.12,12:1:4:8.9.11,12:9:4:2.7.1,6:5:11:2.1.12|
Structure:
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