Reaction Details
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Neuronal acetylcholine receptor subunit alpha-6
Ligand
BDBM86242
Substrate
n/a
Ki
7700±n/a nM
Comments
PDSP_1928
Citation
Vailati, S; Moretti, M; Longhi, R; Rovati, GE; Clementi, F; Gotti, C Developmental expression of heteromeric nicotinic receptor subtypes in chick retina. Mol Pharmacol 63:1329-37 (2003) [PubMed] Article More Info.:
Target
Name:
Neuronal acetylcholine receptor subunit alpha-6
Synonyms:
ACHA6_CHICK | CHRNA6 | Cholinergic, Nicotinic Alpha6
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57501.33
Organism:
Chick
Description:
Cholinergic, Nicotinic Alpha6 0 Chick::P49581
Residue:
494
Sequence:
MHPKRRLCWCLPASGAWAFMLTSLIADTTACESEERLFHKLFSRYNQFIRPVENVSDPVTVHFELAITQLTNVDEVNQIMETNLWLRHIWNDYKLRRDPREYDGIEFVRVPADKIWKPDIVLYNNAVGDFQVEGKTKALLRYDGMITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAKIDLLIIGSKVDMNEFWENSEWEIVDASGYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVITVFVLNIHYRTPTTHTMPKWVKTVFLSLLPKVLLMQRPLEQEKKNISKKTKKGSAKTSGKSKHSKHKDNKLHKEQRCCHCDKADDLTSTRRSRLSHQSLKWMAEHTEYSPEVKDVINNVQFIAENMKSQNETKEVEDDWKYVAMVIDRVFLWVFIILCVFGTAGLFIQPLIADT
Inhibitor
Name:
BDBM86242
Synonyms:
CAS_64645 | NSC_64645 | Tubocurarine,d
Type:
Small organic molecule
Emp. Form.:
C37H42N2O6
Mol. Mass.:
610.7381
SMILES:
COc1cc2CC[N+](C)(C)C3Cc4ccc(O)c(Oc5cc6C(Cc7ccc(Oc(c1O)c23)cc7)[NH+](C)CCc6cc5OC)c4
Structure:
